CB-6673567 | AC1 inhibitor | Probechem Biochemicals

Chemical Structure : CB-6673567

CB-6673567 (CB6673567)

Catalog No.: PC-62711Not For Human Use, Lab Use Only.

CB-6673567 is a potent, selective Adenylyl Cyclase 1 (AC1) inhibitor with IC50 of 77 uM, displays a 2- to 4-fold isoform selectivity over AC6.

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Biological Activity

CB-6673567 is a potent, selective Adenylyl Cyclase 1 (AC1) inhibitor with IC50 of 77 uM, displays a 2- to 4-fold isoform selectivity over AC6; blocks the choline-induced cAMP increase in hippocampal neurons.

Physicochemical Properties

M.Wt	346.346
Formula	C19H14N4O3
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	1,3-Benzodioxol-4-ol, 5-(1'-phenyl[4,4'-bi-1H-pyrazol]-3-yl)-

References

1. Brand CS, et al. J Pharmacol Exp Ther. 2013 Nov;347(2):265-75.

2. Cheng Q, et al. Neuropharmacology. 2015 Aug;95:405-14.

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CB-6673567 (CB6673567)

Biological Activity

Physicochemical Properties

References

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