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CB253

Chemical Structure : CB253

CAS No.: 1225169-17-4

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CB253 (CB 253)

Catalog No.: PC-73396Not For Human Use, Lab Use Only.

CB253 is a small molecule that selectively binds the hairpin form of r(G4C2)exp, inhibiting mechanisms that drive c9ALS/FTD pathobiology.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

CB253 is a small molecule that selectively binds the hairpin form of r(G4C2)exp, inhibiting mechanisms that drive c9ALS/FTD pathobiology.

Physicochemical Properties

M.Wt 310.357
Formula C17H18N4O2
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

N2-(2,4-dimethoxyphenyl)-N4-methylquinazoline-2,4-diamine

References

1. Ursu A, et al. ACS Chem Neurosci. 2021 Nov 3;12(21):4076-4089.

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