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Chemical Structure : CB2 agonist 4Q3C
CAS No.: 103914-79-0
Catalog No.: PC-23401Not For Human Use, Lab Use Only.
4Q3C is a selective CB2 receptor agonist, has selectivity index 10,000 more over CB1.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 5 mg | $198 | In stock | |
| 10 mg | $298 | In stock | |
| 25 mg | $488 | In stock | |
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4Q3C is a selective CB2 receptor agonist, has selectivity index 10,000 more over CB1.
4Q3C significantly inhibits the mechanosensitivity of mucosal bladder afferents to stroking.
4Q3C significantly reduces the severity of arthritis, decreased histopathological findings, and markedly reduced bone erosion in collagen-induced arthritis (CIA) mice.
4Q3C prevents an increase in the nuclear factor-κB ligand (RANKL)/osteoprotegerin (OPG) ratio and inhibits the formation of osteoclasts in CIA mice.
| M.Wt | 188.19 | |
| Formula | C10H8N2O2 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
|
| Chemical Name/SMILES |
4-quinolone-3-carboxyamide |
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1. Bai J, et al. Biomed Pharmacother. 2019 Aug;116:109025.
2. Christie S, et al. Am J Physiol Renal Physiol. 2021 May 1;320(5):F859-F865.
3. Pasquini S, et al. J Med Chem 54: 5444-5453, 2011.
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