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Chemical Structure : CB5305630
Catalog No.: PC-70079Not For Human Use, Lab Use Only.
CB5305630 is a potent and noncompetitive IRE1 RNase inhibitor with IC50 of 60 nM in the FRET-derepression assay.
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CB5305630 is a potent and noncompetitive IRE1 RNase inhibitor with IC50 of 60 nM in the FRET-derepression assay.
CB5305630 also inhibits the cleavage of a radiolabeled Xbp1-derived RNA probe in vitro.
| M.Wt | 280.278 | |
| Formula | C16H12N2O3 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Cross BC, et al. Proc Natl Acad Sci U S A. 2012 Apr 10;109(15):E869-78.
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