CBP bromodomain inhibitor 29 | CBP bromodomain inhibitor

Chemical Structure : CBP bromodomain inhibitor 29

CBP bromodomain inhibitor 29 (CBP-IN-29)

Catalog No.: PC-21985Not For Human Use, Lab Use Only.

CBP-IN-29 is a potent, selective CBP bromodomain inhibitor with IC50 of 2.2 nM, displays exquisite selectivity over BRD4(1) (IC50=23 uM) and the broader bromodomain family.

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Biological Activity

CBP-IN-29 is a potent, selective CBP bromodomain inhibitor with IC50 of 2.2 nM, displays exquisite selectivity over BRD4(1) (IC50=23 uM) and the broader bromodomain family.

Physicochemical Properties

M.Wt	478.55
Formula	C26H28F2N6O
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	5-(7-(Difluoromethyl)-6-(1-methyl-1H-pyrazol-4-yl)-3,4-dihydroquinolin-1(2H)-yl)-7-isopropyl-N-methyl-1H-pyrrolo[2,3-c]pyridine-3-carboxamide

References

1. Bronner SM, et al. J Med Chem. 2017 Dec 28;60(24):10151-10171.

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CBP bromodomain inhibitor 29 (CBP-IN-29)

Biological Activity

Physicochemical Properties

References

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