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CBX6 inhibitor 5

Chemical Structure : CBX6 inhibitor 5

CAS No.:

CBX6 inhibitor 5

Catalog No.: PC-72298Not For Human Use, Lab Use Only.

CBX6 inhibitor 5 is a selective inhibitor of methyllysine reader protein CBX6 with Kd of 0.9 uM, 90×, 20×, 18×, 6×, and 7× selective for CBX6 over CBX1/2/4/7/8, respectively.

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    Biological Activity

    CBX6 inhibitor 5 is a selective inhibitor of methyllysine reader protein CBX6 with Kd of 0.9 uM, 90×, 20×, 18×, 6×, and 7× selective for CBX6 over CBX1/2/4/7/8, respectively.

    Physicochemical Properties

    M.Wt 1125.152
    Formula C53H76BrN10O12+
    Appearance Solid
    CAS No.
    Storage
    Solide Powder
    -20°C 12 Months; 4°C 6 Months
    In Solvent
    -80°C 6 Months; -20°C 6 Months
    Shipping
    Solubility

    Chemical Name/SMILES

    (3S,6S,9S,12S)-3-benzyl-1-(4-bromophenyl)-12-(((S)-1-(((S)-4-carboxy-1-(((S)-1,6-diamino-1-oxohexan-2-yl)amino)-1-oxobutan-2-yl)amino)-3-hydroxy-1-oxopropan-2-yl)carbamoyl)-9-(4-hydroxybenzyl)-6-isopropyl-N,N,N-trimethyl-1,4,7,10-tetraoxo-2,5,8,11-tetraazahexadecan-16-aminium

    References

    1. Natalia Milosevich, et al. ACS Med Chem Lett. 2015 Dec 7;7(2):139-44.

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