CC-410 | NNMT inhibitor | Probechem Biochemicals

Chemical Structure : CC-410

CC-410 (CC410)

Catalog No.: PC-20846Not For Human Use, Lab Use Only.

CC-410 (CC410) is a potent, specific inhibitor of nicotinamide N-methyltransferase (NNMT) with IC50 of 1.6 uM (human NNMT).

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Biological Activity

CC-410 (CC410) is a potent, specific inhibitor of nicotinamide N-methyltransferase (NNMT) with IC50 of 1.6 uM (human NNMT).
CC-410 slightly inhibits PRMT3, SET1b Complex and SMYD2 with IC50 of 104, 120 and 34.25 uM respectively.
CC-410 (25 uM) impairs terminal adipocyte differentiation by blocking the GC signaling cascade in post confluent 3T3-L1 cells.

Physicochemical Properties

M.Wt	462.68
Formula	C27H46N2O4
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	C[C@H]([C@@H]1CC[C@]2([H])[C@@]3([H])[C@@H](N)C[C@@]4([H])C[C@@H](OC(C)=O)CC[C@@]4(C)C3C[C@@H](N)[C@@]12C)CCC(OC)=O

References

1. Annalisa Roberti, et al. Sci Rep. 2023 May 22;13(1):8293.

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CC-410 (CC410)

Biological Activity

Physicochemical Properties

References

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