CCR1 inhibitor 19e |CAS:1220026-26-5 Probechem Biochemicals

Chemical Structure : CCR1 inhibitor 19e

CAS No.: 1220026-26-5

Catalog No.: PC-35940Not For Human Use, Lab Use Only.

CCR1 inhibitor 19e is a novel potent, selective CCR1 antagonist with IC50 of 6.8 nM, inhibits CCR1chemotaxis in THP-1 cells with IC50 of 28 nM..

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Biological Activity

CCR1 inhibitor 19e is a novel potent, selective CCR1 antagonist with IC50 of 6.8 nM, inhibits CCR1chemotaxis in THP-1 cells with IC50 of 28 nM.

M.Wt	425.438
Formula	C20H16FN5O3S
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	1-(4-fluorophenyl)-N-((2-(methylsulfonyl)pyridin-4-yl)methyl)-1H-pyrazolo[3,4-c]pyridine-4-carboxamide

1. Harcken C, et al. Bioorg Med Chem Lett. 2018 Dec 13. pii: S0960-894X(18)30958-2. doi: 10.1016/j.bmcl.2018.12.024.