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CCR7 inhibitor 30c

Chemical Structure : CCR7 inhibitor 30c

CAS No.:

CCR7 inhibitor 30c

Catalog No.: PC-20971Not For Human Use, Lab Use Only.

CCR7 inhibitor 30c is a potent, selective CC chemokine receptor 7 (CCR7) antagonist with IC50 of 0.43 uM, 25-fold selectivity over CXCR2.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

    Biological Activity

    CCR7 inhibitor 30c is a potent, selective CC chemokine receptor 7 (CCR7) antagonist with IC50 of 0.43 uM, 25-fold selectivity over CXCR2.

    Physicochemical Properties

    M.Wt 310.42
    Formula C13H22N6OS
    Appearance Solid
    CAS No.
    Storage
    Solide Powder
    -20°C 12 Months; 4°C 6 Months
    In Solvent
    -80°C 6 Months; -20°C 6 Months
    Shipping
    Solubility

    10 mM in DMSO

    Chemical Name/SMILES

    (R)-2-((5-(hexylthio)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-7-yl)amino)propan-1-ol

    References

    1. Max Van Hoof, et al. Eur J Med Chem. 2023 May 5;251:115240.

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