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CCR7 inhibitor 30c

Chemical Structure : CCR7 inhibitor 30c

CAS No.:

CCR7 inhibitor 30c

Catalog No.: PC-20971Not For Human Use, Lab Use Only.

CCR7 inhibitor 30c is a potent, selective CC chemokine receptor 7 (CCR7) antagonist with IC50 of 0.43 uM, 25-fold selectivity over CXCR2.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

CCR7 inhibitor 30c is a potent, selective CC chemokine receptor 7 (CCR7) antagonist with IC50 of 0.43 uM, 25-fold selectivity over CXCR2.

Physicochemical Properties

M.Wt 310.42
Formula C13H22N6OS
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

C[C@@H](NC1=C(N=NN2)C2=NC(SCCCCCC)=N1)CO

References

1. Max Van Hoof, et al. Eur J Med Chem. 2023 May 5;251:115240.

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