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CCR9 inhibitor 12

Chemical Structure : CCR9 inhibitor 12

CAS No.: 1943654-87-2

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CCR9 inhibitor 12

Catalog No.: PC-38757Not For Human Use, Lab Use Only.

CCR9 inhibitor 12 is a potent inhibitor of chemokine receptor 9 (CCR9) with IC50 of 20 nM in calcium (Ca2+) FLIPR assay, shows IC50 of 277 nM in chemotaxis assays.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

    Biological Activity

    CCR9 inhibitor 12 is a potent inhibitor of chemokine receptor 9 (CCR9) with IC50 of 20 nM in calcium (Ca2+) FLIPR assay, shows IC50 of 277 nM in chemotaxis assays.

    Physicochemical Properties

    M.Wt 342.823
    Formula C19H19ClN2O2
    Appearance Solid
    CAS No.
    Storage
    Solide Powder
    -20°C 12 Months; 4°C 6 Months
    In Solvent
    -80°C 6 Months; -20°C 6 Months
    Shipping
    Solubility

    10 mM in DMSO
    Chemical Name/SMILES

    1-(4-(tert-butyl)benzyl)-6-chloro-1H-pyrrolo[3,2-b]pyridine-2-carboxylic acid

    References

    1. Pandya BA, et al. Bioorg Med Chem Lett. 2016 Jul 15;26(14):3322-3325.

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