Chemical Structure : CCT-251921
CAS No.:
1607837-31-9
CCT-251921
(CCT 251921, CCT251921)
Catalog No. : PC-61146Not For Human Use, Lab Use Only.
CCT-251921 (CCT251921) is a potent, selective, and orally bioavailable inhibitor of CDK8 and CDK19 with IC50of 2.3 nM and 2.6 nM respectively.
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Purity & Documentation Purity:
>98% (HPLC) Select Batch: PC-6114601
Biological Activity
CCT-251921 (CCT251921) is a potent, selective, and orally bioavailable inhibitor of CDK8 and CDK19 with IC50of 2.3 nM and 2.6 nM respectively.
Physicochemical Properties
M.Wt
410.906
Formula
C21H23ClN6O
Appearance
Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility
10 mM in DMSO
Chemical Name/SMILES
8-(2-Amino-3-chloro-5-(1-methyl-1H-indazol-5-yl)pyridin-4-yl)-2,8-diazaspiro[4.5]decan-1-one
References
1. Mallinger A, et al. J Med Chem.
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