Chemical Structure : CCT 137690
CAS No.:
1095382-05-0
CCT 137690
(CCT-137690;CCT137690)
Catalog No. : PC-42703Not For Human Use, Lab Use Only.
CCT 137690 is a potent, orally bioavailable Aurora kinases inhibitor with IC50 of 15/25/19 nM for Aurora A/B/C, respectively.
Packing Price Stock Quantity 5 mg $78 In stock 0 1 2 3 4 5 10 mg $118 In stock 0 1 2 3 4 5 25 mg $198 In stock 0 1 2 3 4 5 50 mg $328 In stock 0 1 2 3 4 5 100 mg $528 In stock 0 1 2 3 4 5 250 mg Get quote 0 1 2 3 4 5
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Purity & Documentation Purity:
>98% (HPLC) Select Batch: PC-4270301
Biological Activity
CCT 137690 is a potent, orally bioavailable Aurora kinases inhibitor with IC50 of 15/25/19 nM for Aurora A/B/C, respectively.
Physicochemical Properties
M.Wt
551.4813
Formula
C26H31BrN8O
Appearance
Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility
10 mM in DMSO
Chemical Name/SMILES
3H-Imidazo[4,5-b]pyridine, 6-bromo-7-[4-[(5-methyl-3-isoxazolyl)methyl]-1-piperazinyl]-2-[4-(4-methyl-1-piperazinyl)phenyl]-
References
1. Bavetsias V, et al. J Med Chem
2. Faisal A, et al. Mol Cancer Ther.
3. Moore AS, et al. Leukemia
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