Chemical Structure : CCT241533
CAS No.:
1262849-73-9
CCT241533
(CCT 241533;CCT-241533)
Catalog No. : PC-44032Not For Human Use, Lab Use Only.
CCT241533 is a potent and selective ATP-competitive inhibitor of CHK2 with IC50 of 3 nM.
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Purity & Documentation Purity:
>98% (HPLC) Select Batch: PC-4403201
Biological Activity
CCT241533 is a potent and selective ATP-competitive inhibitor of CHK2 with IC50 of 3 nM.
Physicochemical Properties
M.Wt
442.4833
Formula
C23H27FN4O4
Appearance
Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility
10 mM in DMSO
Chemical Name/SMILES
3-Pyrrolidinemethanol, 4-[[2-(5-fluoro-2-hydroxyphenyl)-6,7-dimethoxy-4-quinazolinyl]amino]-α,α-dimethyl-, (3R,4S)-
References
1. Caldwell JJ, et al. J Med Chem
2. Anderson VE, et al. Cancer Res.
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