Chemical Structure : CCT241533 hydrochloride
CAS No.:
1431697-96-9
CCT241533 hydrochloride
(CCT-241533 hydrochloride;CCT 241533 hydrochloride)
Catalog No. : PC-44033Not For Human Use, Lab Use Only.
CCT241533 hydrochloride is a potent and selective ATP-competitive inhibitor of CHK2 with IC50 of 3 nM.
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Purity & Documentation Purity:
>98% (HPLC) Select Batch: PC-4403301
Biological Activity
CCT241533 hydrochloride is a potent and selective ATP-competitive inhibitor of CHK2 with IC50 of 3 nM.
Physicochemical Properties
M.Wt
478.9442
Formula
C23H28ClFN4O4
Appearance
Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility
10 mM in DMSO
Chemical Name/SMILES
4-fluoro-2-(4-(((3S,4R)-4-(2-hydroxypropan-2-yl)pyrrolidin-3-yl)amino)-6,7-dimethoxyquinazolin-2-yl)phenol hydrochloride
References
1. Caldwell JJ, et al. J Med Chem.
2. Anderson VE, et al. Cancer Res.
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