CD 1530 |CAS:107430-66-0 Probechem Biochemicals

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Chemical Structure : CD 1530

CD 1530 (CD-1530;CD1530)

Catalog No.: PC-70289Not For Human Use, Lab Use Only.

CD 1530 is a potent and selective RARγ receptor agonist with Ki of 150 nM, >10-fold less potent for RARβ and RARα.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

CD 1530 is a potent and selective RARγ receptor agonist with Ki of 150 nM, >10-fold less potent for RARβ and RARα.
CD 1530 also is a potent an inhibitor of CYP26A1 as ketoconazole with IC50 of 530 nM.

Physicochemical Properties

M.Wt	398.49
Formula	C27H26O3
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	4-(6-Hydroxy-7-tricyclo[3.3.1.13,7]dec-1-yl-2-naphthalenyl)benzoic acid

References

1. Tang XH, et al. Proc Natl Acad Sci U S A. 2014 Jun 17;111(24):8907-12.

2. Thatcher JE, et al. Mol Pharmacol. 2011 Aug;80(2):228-39.

3. Duprey-Díaz MV, et al. PLoS One. 2016 Sep 9;11(9):e0162626.

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CD 1530 (CD-1530;CD1530)

Biological Activity

Physicochemical Properties

References

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