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CD 1530

Chemical Structure : CD 1530

CAS No.: 107430-66-0

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CD 1530 (CD-1530;CD1530)

Catalog No.: PC-70289Not For Human Use, Lab Use Only.

CD 1530 is a potent and selective RARγ receptor agonist with Ki of 150 nM, >10-fold less potent for RARβ and RARα.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

    Biological Activity

    CD 1530 is a potent and selective RARγ receptor agonist with Ki of 150 nM, >10-fold less potent for RARβ and RARα.
    CD 1530  also is a potent an inhibitor of CYP26A1 as ketoconazole with IC50 of 530 nM.

    Physicochemical Properties

    M.Wt 398.49
    Formula C27H26O3
    Appearance Solid
    CAS No.
    Storage
    Solide Powder
    -20 °C 12 Months; 4°C 6 Months
    In Solvent
    -80 °C 6 Months; -20°C 6 Months
    Shipping
    Solubility

    10 mM in DMSO
    Chemical Name/SMILES

    4-(6-Hydroxy-7-tricyclo[3.3.1.13,7]dec-1-yl-2-naphthalenyl)benzoic acid

    References

    1. Tang XH, et al. Proc Natl Acad Sci U S A. 2014 Jun 17;111(24):8907-12.

    2. Thatcher JE, et al. Mol Pharmacol. 2011 Aug;80(2):228-39.

    3. Duprey-Díaz MV, et al. PLoS One. 2016 Sep 9;11(9):e0162626.

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