CD2665 | RARγ inhibitor | Probechem Biochemicals

Chemical Structure : CD2665

CAS No.: 170355-78-9

CD2665 (CD 2665)

Catalog No.: PC-21835Not For Human Use, Lab Use Only.

CD2665 is a potent, selective and orally active RAR-β/ RAR-γ antagonist with Ki of 306 and 110 nM, respectively.

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Biological Activity

CD2665 is a potent, selective and orally active RAR-β/ RAR-γ antagonist with Ki of 306 and 110 nM, respectively.
CD2665 inhibits RA receptor-dependent gene transcription, blocks retinoid induction of RA 4-hydroxylase.

Physicochemical Properties

M.Wt	486.61
Formula	C31H34O5
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	4-(7-(adamantan-1-yl)-6-((2-methoxyethoxy)methoxy)naphthalen-2-yl)benzoic acid

References

1. Kim MJ, et al. J Invest Dermatol. 2000 Feb;114(2):349-53.

2. Koyama E, et al. J Bone Miner Res. 2021 Jul;36(7):1387-1402.

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CD2665 (CD 2665)

Biological Activity

Physicochemical Properties

References

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