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CD3254

Chemical Structure : CD3254

CAS No.: 196961-43-0

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CD3254 (CD-3254, CD 3254)

Catalog No.: PC-20829Not For Human Use, Lab Use Only.

CD3254 (CD 3254) is a potent and selective RXR agonist with EC50 of 13 nM.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

CD3254 (CD 3254) is a potent and selective RXR agonist with EC50 of 13 nM.
CD3254 stimulates RXR-regulated transcription in mammalian 2 hybrid and RXRE-mediated assays.

Physicochemical Properties

M.Wt 364.49
Formula C24H28O3
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

(E)-3-[3-(3,5,5,8,8-pentamethyl-5,6,7,8-tetrahydronaphthalen-2-yl)-4-hydroxyphenyl]acrylic acid

References

1. Jin Y, et al. Proc Natl Acad Sci U S A. 2023 May 23;120(21):e2215155120.

2. Pérez Santín E, et al. J Med Chem. 2009 May 28;52(10):3150-8.

3. Bernardon JM. Int Patent Appl. 1997 WO9733881.

4. Jurutka PW, et al. J Med Chem. 2013 Nov 14;56(21):8432-54.

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