Chemical Structure : CD3254
CAS No.: 196961-43-0
Catalog No.: PC-20829Not For Human Use, Lab Use Only.
CD3254 (CD 3254) is a potent and selective RXR agonist with EC50 of 13 nM.
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CD3254 (CD 3254) is a potent and selective RXR agonist with EC50 of 13 nM.
CD3254 stimulates RXR-regulated transcription in mammalian 2 hybrid and RXRE-mediated assays.
M.Wt | 364.49 | |
Formula | C24H28O3 | |
Appearance | Solid | |
Storage |
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Solubility |
10 mM in DMSO |
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Chemical Name/SMILES |
(E)-3-[3-(3,5,5,8,8-pentamethyl-5,6,7,8-tetrahydronaphthalen-2-yl)-4-hydroxyphenyl]acrylic acid |
1. Jin Y, et al. Proc Natl Acad Sci U S A. 2023 May 23;120(21):e2215155120.
2. Pérez Santín E, et al. J Med Chem. 2009 May 28;52(10):3150-8.
3. Bernardon JM. Int Patent Appl. 1997 WO9733881.
4. Jurutka PW, et al. J Med Chem. 2013 Nov 14;56(21):8432-54.
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