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Chemical Structure : CDDO-Im
CAS No.: 443104-02-7
Catalog No.: PC-44663Not For Human Use, Lab Use Only.
A potent Nrf2 activator that elevates protein levels of Nrf2 and induces Nrf2/ARE signaling.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 10 mg | $152 | In stock | |
| 50 mg | $425 | In stock |
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A potent Nrf2 activator that elevates protein levels of Nrf2 and induces Nrf2/ARE signaling; induced Ahr, Cyp1a1, and Cyp1b1 transcription in Nrf2+/+ MEFs but not in Nrf2-/- MEFs; significantly reduces lung oxidative stress, alveolar cell apoptosis, alveolar destruction, and pulmonary hypertension in Nrf2(+/+) mice.
| M.Wt | 541.7235 | |
| Formula | C34H43N3O3 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
|
| Chemical Name/SMILES |
1H-Imidazole, 1-(2-cyano-3,12,28-trioxooleana-1,9(11)-dien-28-yl)- |
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1. Liby K, et al. Cancer Res. 2005 Jun 1;65(11):4789-98.
2. Sussan TE, et al. Proc Natl Acad Sci U S A. 2009 Jan 6;106(1):250-5.
3. Shin S, et al. Mol Cell Biol. 2007 Oct;27(20):7188-97.
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