CDIBA

Chemical Structure : CDIBA

Catalog No.: PC-49683Not For Human Use, Lab Use Only.

CDIBA is an allosteric inhibitors of m6A-RNA methyltransferase, METTL3 -14 complex with IC50 of 17.3 uM, also reported as a cytosolic phospholipase A2 (cPLA2) inhibitor.

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Biological Activity

CDIBA is an allosteric inhibitors of m6A-RNA methyltransferase, METTL3-14 complex with IC50 of 17.3 uM, also reported as a cytosolic phospholipase A2 (cPLA2) inhibitor.

Physicochemical Properties

M.Wt	496.00
Formula	C31H26ClNO3
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	4-(2-(1-benzhydryl-5-chloro-2-methyl-1H-indol-3-yl)ethoxy)benzoic acid

References

1. Je-Heon Lee, et al. Drug Dev Res. 2022 May;83(3):783-799.

2. Supinski GS,et al. Am J Physiol Lung Cell Mol Physiol. 2016 May 15;310(10):L975-84.

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CDIBA

Biological Activity

Physicochemical Properties

References

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