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CDIBA

Chemical Structure : CDIBA

CAS No.: 479422-22-5

CDIBA

Catalog No.: PC-49683Not For Human Use, Lab Use Only.

CDIBA is an allosteric inhibitors of m6A-RNA methyltransferase, METTL3 -14 complex with IC50 of 17.3 uM, also reported as a cytosolic phospholipase A2 (cPLA2) inhibitor.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

    Biological Activity

    CDIBA is an allosteric inhibitors of m6A-RNA methyltransferase, METTL3-14 complex with IC50 of 17.3 uM, also reported as a cytosolic phospholipase A2 (cPLA2) inhibitor.

    Physicochemical Properties

    M.Wt 496.00
    Formula C31H26ClNO3
    Appearance Solid
    CAS No.
    Storage
    Solide Powder
    -20°C 12 Months; 4°C 6 Months
    In Solvent
    -80°C 6 Months; -20°C 6 Months
    Shipping
    Solubility

    10 mM in DMSO

    Chemical Name/SMILES

    4-(2-(1-benzhydryl-5-chloro-2-methyl-1H-indol-3-yl)ethoxy)benzoic acid

    References

    1. Je-Heon Lee, et al. Drug Dev Res. 2022 May;83(3):783-799.

    2. Supinski GS,et al. Am J Physiol Lung Cell Mol Physiol. 2016 May 15;310(10):L975-84.

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