CDK8 inhibitor 32

Chemical Structure : CDK8 inhibitor 32

Catalog No.: PC-20219Not For Human Use, Lab Use Only.

CDK8 inhibitor 32 is a potent selective CDK8 inhibitor with IC50 of 1.5 nM, reduces phosphorylation of the known CDK8 substrate STAT1 in a manner identical to a CDK8 knockout clone.

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Biological Activity

CDK8 inhibitor 32 is a potent selective CDK8 inhibitor with IC50 of 1.5 nM, reduces phosphorylation of the known CDK8 substrate STAT1 in a manner identical to a CDK8 knockout clone.

Physicochemical Properties

M.Wt	319.76
Formula	C14H10ClN3O2S
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	7-amino-4-(4-chlorophenoxy)thieno[2,3-c]pyridine-2-carboxamide

References

1. Koehler MF, et al. ACS Med Chem Lett. 2016 Jan 6;7(3):223-8.

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