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CDK8 inhibitor 32

Chemical Structure : CDK8 inhibitor 32

CAS No.: 1855853-51-8

CDK8 inhibitor 32

Catalog No.: PC-20219Not For Human Use, Lab Use Only.

CDK8 inhibitor 32 is a potent selective CDK8 inhibitor with IC50 of 1.5 nM, reduces phosphorylation of the known CDK8 substrate STAT1 in a manner identical to a CDK8 knockout clone.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

    Biological Activity

    CDK8 inhibitor 32 is a potent selective CDK8 inhibitor with IC50 of 1.5 nM, reduces phosphorylation of the known CDK8 substrate STAT1 in a manner identical to a CDK8 knockout clone.

    Physicochemical Properties

    M.Wt 319.76
    Formula C14H10ClN3O2S
    Appearance Solid
    CAS No.
    Storage
    Solide Powder
    -20°C 12 Months; 4°C 6 Months
    In Solvent
    -80°C 6 Months; -20°C 6 Months
    Shipping
    Solubility

    10 mM in DMSO

    Chemical Name/SMILES

    7-amino-4-(4-chlorophenoxy)thieno[2,3-c]pyridine-2-carboxamide

    References

    1. Koehler MF, et al. ACS Med Chem Lett. 2016 Jan 6;7(3):223-8.

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