CDK9-IN-1 |CAS:1415559-43-1 Probechem Biochemicals

Chemical Structure : CDK9-IN-1

CAS No.: 1415559-43-1

CDK9-IN-1

Catalog No.: PC-43411Not For Human Use, Lab Use Only.

CDK9-IN-1 is a potent, selective CDK9 inhibitor with IC50 of 39 nM (CDK9/CycT1), >10-fold selectivity over CDK4 and >100-fold over CDK1/2/3/5/6/7, inhibits HIV-1 replication in cellular assays.

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Biological Activity

CDK9-IN-1 is a potent, selective CDK9 inhibitor with IC50 of 39 nM (CDK9/CycT1), >10-fold selectivity over CDK4 and >100-fold over CDK1/2/3/5/6/7, inhibits HIV-1 replication in cellular assays.

Physicochemical Properties

M.Wt	499.541
Formula	C26H21N5O4S
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	N-(5-(6-(3-(1,3-dioxoisoindolin-2-yl)phenyl)pyrimidin-4-ylamino)-2-methylphenyl)methanesulfonamide

References

1. Németh G, et al. Curr Med Chem. 2011;18(3):342-58.

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CDK9-IN-1

Biological Activity

Physicochemical Properties

References

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