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CDK9-IN-1

Chemical Structure : CDK9-IN-1

CAS No.: 1415559-43-1

CDK9-IN-1

Catalog No.: PC-43411Not For Human Use, Lab Use Only.

CDK9-IN-1 is a potent, selective CDK9 inhibitor with IC50 of 39 nM (CDK9/CycT1), >10-fold selectivity over CDK4 and >100-fold over CDK1/2/3/5/6/7, inhibits HIV-1 replication in cellular assays.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

CDK9-IN-1 is a potent, selective CDK9 inhibitor with IC50 of 39 nM (CDK9/CycT1), >10-fold selectivity over CDK4 and >100-fold over CDK1/2/3/5/6/7, inhibits HIV-1 replication in cellular assays.

Physicochemical Properties

M.Wt 499.541
Formula C26H21N5O4S
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

N-(5-(6-(3-(1,3-dioxoisoindolin-2-yl)phenyl)pyrimidin-4-ylamino)-2-methylphenyl)methanesulfonamide

References

1. Németh G, et al. Curr Med Chem. 2011;18(3):342-58.

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