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Chemical Structure : CDK9-IN-4d
Catalog No.: PC-62848Not For Human Use, Lab Use Only.
CDK9-IN-1 is a highly potent, selective CDK9 inhibitor with IC50 of 12 nM, shows good selectivity in CDKs kinase profiling assay against CDK kinases and cell proliferation inhibition.
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CDK9-IN-1 is a highly potent, selective CDK9 inhibitor with IC50 of 12 nM, shows good selectivity in CDKs kinase profiling assay against CDK kinases and cell proliferation inhibition; blocks the cell cycle both in G0/G1 and G2/M phase to prevent the proliferation and differentiation of cancer cells; significantly suppresses cancer with low toxicity in mice bared-breast cancer.
| M.Wt | 569.641 | |
| Formula | C31H32FN7O3 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Li Y, et al. Bioorg Med Chem Lett. 2017 Aug 1;27(15):3231-3237.
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