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Chemical Structure : CDPPB
CAS No.: 781652-57-1
Catalog No.: PC-62955Not For Human Use, Lab Use Only.
CDPPB is a potent, selective, brain penetrant positive allosteric modulator of mGlu5 receptor with EC50 of 10 nM and 20 nM for human and rat mGluR5, respectively.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 5 mg | $88 | In stock | |
| 10 mg | $128 | In stock | |
| 25 mg | $218 | In stock | |
| 50 mg | $358 | In stock | |
| 100 mg | Get quote |
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CDPPB is a potent, selective, brain penetrant positive allosteric modulator of mGlu5 receptor with EC50 of 10 nM and 20 nM for human and rat mGluR5, respectively.
CDPPB reverses amphetamine-induced locomotor activity and amphetamine-induced deficits in prepulse inhibition in rats.
| M.Wt | 364.408 | |
| Formula | C23H16N4O | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
|
| Chemical Name/SMILES |
3-cyano-N-(1,3-diphenyl-1H-pyrazol-5-yl)benzamide |
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1. Kinney GG, et al. J Pharmacol Exp Ther. 2005 Apr;313(1):199-206.
2. Chen Y, et al. Mol Pharmacol. 2007 May;71(5):1389-98.
3. Lindsley CW, et al. J Med Chem. 2004 Nov 18;47(24):5825-8.
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