Chemical Structure : CFI-402257
CAS No.:
1610759-22-2
CFI-402257
(CFI402257)
Catalog No. : PC-42354Not For Human Use, Lab Use Only.
CFI-402257 (CFI 402257) is a potent and selective Mps1/TTK kinase inhibitor with Ki of 0.1 nM and cellular Mps1 EC50 of 6.5 nM.
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Purity & Documentation Purity:
>98% (HPLC) Select Batch: PC-4235401
Biological Activity
CFI-402257 (CFI 402257) is a potent and selective Mps1 /TTK kinase inhibitor with Ki of 0.1 nM and cellular Mps1 EC50 of 6.5 nM.
Physicochemical Properties
M.Wt
498.58
Formula
C28H30N6O3
Appearance
Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility
DMSO: 10 mM (Need Warming and Ultrasonic)
Chemical Name/SMILES
Benzamide, N-cyclopropyl-4-[7-[[(cis-3-hydroxy-3-methylcyclobutyl)methyl]amino]-5-(3-pyridinyloxy)pyrazolo[1,5-a]pyrimidin-3-yl]-2-methyl-
References
1. Mason JM, et al. Proc Natl Acad Sci U S A.
2. Liu Y, et al. ACS Med Chem Lett.
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