| Cat. No. |
Product Name |
Information |
| PC-38336 |
RMS-07
MPS1/TTK inhibitor
|
RMS-07 (RMS 07) is the first potent, selective irreversible covalent inhibitor of Monopolar spindle kinase 1 (MPS1/TTK) with IC50 of 13 nM, Ki of 0.83 nM. |
| PC-35662 |
BOS172722
MPS1/TTK inhibitor
|
BOS172722 (BOS-172722) is a potent, selective MPS1 kinase (TTK) inhibitor with biochemical IC50 of 11 nM, 100-fold selectivity over CDK2. |
| PC-43476 |
Mps1-IN-1
MPS1/TTK inhibitor
|
Mps1-IN-1 is a potent, selective, ATP-competitive Mps1 kinase inhibitor with IC50 and Kd of 367 nM and 27 nM. |
| PC-43262 |
BAY1217389
MPS1/TTK inhibitor
|
BAY1217389 (BAY-1217389) is a potent, selective Monopolar spindle 1 (Mps1/TTK) inhibitor with IC50 of 0.63 nM. |
| PC-43261 |
Empesertib
MPS1/TTK inhibitor
|
Empesertib (BAY-1161909, BAY1161909) is a potent, selective Monopolar spindle 1 (Mps1/TTK) inhibitor with IC50 of 0.34 nM. |
| PC-43142 |
MPI-0479605
MPS1/TTK inhibitor
|
MPI-0479605 is a potent, selective, ATP competitive inhibitor of Mps1 with IC50 of 1.8 nM. |
| PC-43017 |
Mps1-IN-3
Mps1 inhibitor
|
Mps1-IN-3 is a selective and highly potent Mps1 kinase inhibitor with IC50 of 50 nM. |
| PC-43014 |
NMS-P715
Mps1 inhibitor
|
NMS-P715 is a potent, selective, orally bioavailable Mps1 inhibitor with IC50 of 8 nM, Ki of 0.99 nM. |
| PC-62727 |
CFI-401980
MPS1/TTK inhibitor
|
CFI-401980 is a potent, selective, novel class TTK (Tyrosine Threonine Kinase, MPS1) inhibitor with Ki of 0.8 nM, HCT116 GI50 of 13 nM. |
| PC-62240 |
Mps1 inhibitor 2
MPS1/TTK inhibitor
|
Mps1 inhibitor 2 (Mps1-IN-2) is a potent, selective Mps1 kinase inhibitor with IC50 of 145 nM, demonstrates >1,000-fold selectivity over a panel of 352 kinases with the major exceptions of Gak and Plk1. |
| PC-61464 |
NTRC 0066-0
MPS1/TTK inhibitor
|
NTRC 0066-0 is a highly potent, selective inhibitor of checkpoint kinase TTK/Mps1 with IC50 of 0.6 nM. |
| PC-61144 |
CCT-251455
MPS1/TTK inhibitor
|
CCT-251455 is a potent, selective, orally active monopolar spindle 1 (MPS1) inhibitor with IC50 of 3 nM, with no activity for CDK2 and Aurora A (IC50>40 uM). |
