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CGP-25454A

Chemical Structure : CGP-25454A

CAS No.: 104391-26-6

CGP-25454A (CGP25454A;CGP 25454A)

Catalog No.: PC-42161Not For Human Use, Lab Use Only.

A potent, selective presynaptic dopamine autoreceptor antagonist.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

A potent, selective presynaptic dopamine autoreceptor antagonist; increases [3H]spiperone binding to receptors of the D2 family in rat striatum by 90-110% (ED50=13 mg/kg i.p.); exerts clear-cut sedative and neuroleptic-like properties.

Physicochemical Properties

M.Wt 346.2521
Formula C15H21Cl2N3O2
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

DMSO: ≥ 3.5 mg/mL

Chemical Name/SMILES

Benzamide, 4-chloro-5-cyano-N-[2-(diethylamino)ethyl]-2-methoxy-, hydrochloride (1:1)

References

1. Bischoff S, et al. Naunyn Schmiedebergs Arch Pharmacol. 1994 Sep;350(3):230-8.

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