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Chemical Structure : CGS 21680
CAS No.: 120225-54-9
Catalog No.: PC-43385Not For Human Use, Lab Use Only.
CGS 21680 is a specific adenosine A2A subtype receptor agonist with Ki of 27 nM.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 5 mg | $78 | In stock | |
| 10 mg | $118 | In stock | |
| 25 mg | $198 | In stock | |
| 50 mg | $328 | In stock | |
| 100 mg | Get quote |
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CGS 21680 is a specific adenosine A2A subtype receptor agonist with Ki of 27 nM.
CGS 21680 significantly upregulates CD39 and CD73 expression, accelerates the ATP hydrolysis and adenosine generation.
CGS 21680 reduces the number of infiltrated granulocytes into the ischemic tissue in rat model of transient cerebral ischemia.
| M.Wt | 499.5197 | |
| Formula | C23H29N7O6 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
Benzenepropanoic acid, 4-[2-[[6-amino-9-(N-ethyl-.beta.-D-ribofuranuronamidosyl)-9H-purin-2-yl]amino]ethyl]- |
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1. Nekooeian AA, et al. Br J Pharmacol. 1998 Apr;123(8):1666-72.
2. Phillis JW, et al. Brain Res. 1990 Feb 19;509(2):328-30.
3. Komaki S, et al. Neurosci Lett. 2012 Jul 26;522(1):21-4.
4. Melani A, et al. Brain Res. 2014 Mar 10;1551:59-72.
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