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CHIP ligand 5

Chemical Structure : CHIP ligand 5

CAS No.:

CHIP ligand 5

Catalog No.: PC-25378Not For Human Use, Lab Use Only.

CHIP ligand 5 is potent, small molecule ligand of E3 ligase STUB1 (C-terminus of Hsc70-interacting protein, CHIP) with FP Kd value of 8.92 uM.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

CHIP ligand 5 is potent, small molecule ligand of E3 ligase STUB1 (C-terminus of Hsc70-interacting protein, CHIP) with FP Kd value of 8.92 uM.

Physicochemical Properties

M.Wt 421.41
Formula C17H19F4N3O3S
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

(S)-N,N-dimethyl-1-(1-(4,5,6,7-tetrafluoro-1H-indole-3-carbonyl)piperidin-3-yl)methanesulfonamide

References

1. Lucas SCC, et al. ACS Med Chem Lett. 2025 Aug 5;16(8):1445-1451.

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