Chemical Structure : CIB-3b
CAS No.: 124811-87-6
Catalog No.: PC-38904Not For Human Use, Lab Use Only.
CIB-3b is a small molecule inhibitor disrupting the TRBP-Dicer interaction, suppresses the growth and metastasis of HCC in vitro and in vivo by modulating expression profiles of miRNAome and proteome in HCC cells.
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CIB-3b is a small molecule inhibitor disrupting the TRBP-Dicer interaction, suppresses the growth and metastasis of HCC in vitro and in vivo by modulating expression profiles of miRNAome and proteome in HCC cells.
CIB-3b directly binds to transactivation response (TAR) RNA-binding protein 2 (TRBP), altering the activity of Dicer and mature miRNA production.
M.Wt | 261.277 | |
Formula | C14H15NO4 | |
Appearance | Solid | |
Storage |
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Solubility |
10 mM in DMSO |
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Chemical Name/SMILES |
ethyl 2-(4-methoxyphenyl)-5-methyloxazole-4-carboxylate |
1. Peng T, et al. J Med Chem. 2022 Aug 25;65(16):11010-11033.
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