CID3528206 |CAS:674359-78-5 Probechem Biochemicals

Chemical Structure : CID3528206

CID3528206 (CID 3528206)

Catalog No.: PC-62364Not For Human Use, Lab Use Only.

CID3528206 is a potent, small molecule yeast TORC1 inhibitor that inhibits TORC1 activity both in vitro and in vivo with IC50 of 150 nM and 3.9 uM, respectively.

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Biological Activity

CID3528206 is a potent, small molecule yeast TORC1 inhibitor that inhibits TORC1 activity both in vitro and in vivo with IC50 of 150 nM and 3.9 uM, respectively; alters GFP expression in all five GFP clones in a manner analogous to that of rapamycin, inhibits yeast cell growth.

Physicochemical Properties

M.Wt	278.247
Formula	C11H11FN6O2
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	N4-(3-fluorophenyl)-N2-methyl-5-nitropyrimidine-2,4,6-triamine

References

1. Chen J, et al. ACS Chem Biol. 2012 Apr 20;7(4):715-22.

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CID3528206 (CID 3528206)

Biological Activity

Physicochemical Properties

References

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