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CID3528206

Chemical Structure : CID3528206

CAS No.: 674359-78-5

CID3528206 (CID 3528206)

Catalog No.: PC-62364Not For Human Use, Lab Use Only.

CID3528206 is a potent, small molecule yeast TORC1 inhibitor that inhibits TORC1 activity both in vitro and in vivo with IC50 of 150 nM and 3.9 uM, respectively.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

CID3528206 is a potent, small molecule yeast TORC1 inhibitor that inhibits TORC1 activity both in vitro and in vivo with IC50 of 150 nM and 3.9 uM, respectively; alters GFP expression in all five GFP clones in a manner analogous to that of rapamycin, inhibits yeast cell growth.

Physicochemical Properties

M.Wt 278.247
Formula C11H11FN6O2
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

N4-(3-fluorophenyl)-N2-methyl-5-nitropyrimidine-2,4,6-triamine

References

1. Chen J, et al. ACS Chem Biol. 2012 Apr 20;7(4):715-22.

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