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CID3528206

Chemical Structure : CID3528206

CAS No.: 674359-78-5

CID3528206 (CID 3528206)

Catalog No.: PC-62364Not For Human Use, Lab Use Only.

CID3528206 is a potent, small molecule yeast TORC1 inhibitor that inhibits TORC1 activity both in vitro and in vivo with IC50 of 150 nM and 3.9 uM, respectively.

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    Biological Activity

    CID3528206 is a potent, small molecule yeast TORC1 inhibitor that inhibits TORC1 activity both in vitro and in vivo with IC50 of 150 nM and 3.9 uM, respectively.
    CID3528206 alters GFP expression in all five GFP clones in a manner analogous to that of rapamycin, inhibits yeast cell growth.

    Physicochemical Properties

    M.Wt 278.247
    Formula C11H11FN6O2
    Appearance Solid
    CAS No.
    Storage
    Solide Powder
    -20 °C 12 Months; 4°C 6 Months
    In Solvent
    -80 °C 6 Months; -20°C 6 Months
    Shipping
    Solubility

    10 mM in DMSO

    Chemical Name/SMILES

    N4-(3-fluorophenyl)-N2-methyl-5-nitropyrimidine-2,4,6-triamine

    References

    1. Chen J, et al. ACS Chem Biol. 2012 Apr 20;7(4):715-22.

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