CIDD 0067106 |CAS:2151865-39-1 Probechem Biochemicals

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Chemical Structure : CIDD 0067106

CIDD 0067106 (CIDD0067106)

Catalog No.: PC-62011Not For Human Use, Lab Use Only.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

CIDD 0067106 is a novel natural product-based diaryloxazole that potent and selective antiproliferative activities against androgen receptor-positive breast cancer cells (MDA-MB-453 cell GI50=0.8 uM); displays approximately 37.5- to 62.5-fold antiproliferative selectivity for MDA-MB-453 cells over others TNBC cells (MDA-MB-231 GI50=50 uM); inhibits the activity of the mTORC1 pathway.

Physicochemical Properties

M.Wt	483.99
Formula	C26H30ClN3O4
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	(S)-Methyl-1-[(6-(5-(4-[(3-methylbut-2-en-1-yl)oxy]phenyl)-oxazol-2-yl)pyridin-3-yl)methyl]pyrrolidine-2-carboxylate

References

1. Robles AJ, et al. J Med Chem. 2017 Nov 3. doi: 10.1021/acs.jmedchem.7b01228.

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CIDD 0067106 (CIDD0067106)

Biological Activity

Physicochemical Properties

References

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