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You are here:Home-Chemical Inhibitors & Agonists-Metabolic Enzyme/Protease-Matrix Metalloproteinase (MMP)-CL-82198
CL-82198

Chemical Structure : CL-82198

CAS No.: 307002-71-7

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CL-82198 (CL82198)

Catalog No.: PC-62940Not For Human Use, Lab Use Only.

CL-82198 is a potent, selective inhibitor of MMP-13 (89% inhibition at 10 ug/mL), displays no activity at MMP-1, MMP-9 and TACE, significantly reduces the migration of LS174 cells by 55% at 10 uM..

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25 mg $148 In stock
50 mg $258 In stock
100 mg $388 In stock
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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

CL-82198 is a potent, selective inhibitor of MMP-13 (89% inhibition at 10 ug/mL), displays no activity at MMP-1, MMP-9 and TACE, significantly reduces the migration of LS174 cells by 55% at 10 uM.

Physicochemical Properties

M.Wt 302.374
Formula C17H22N2O3
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

N-[4-(4-morpholinyl)butyl]-2-benzofurancarboxamide

References

1. Chen et al, et al. J.Am.Chem.Soc. 2012.

2. Rath T, et al. Oncol Lett. 2011 May;2(3):483-488.

3. Hernández Ríos M, et al. J Clin Periodontol. 2009 Dec;36(12):1011-7.

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