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CL-82198 hydrochloride

Chemical Structure : CL-82198 hydrochloride

CAS No.: 1188890-36-9

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CL-82198 hydrochloride (CL82198)

Catalog No.: PC-62939Not For Human Use, Lab Use Only.

CL-82198 is a potent, selective inhibitor of MMP-13 (89% inhibition at 10 ug/mL), displays no activity at MMP-1, MMP-9 and TACE, significantly reduces the migration of LS174 cells by 55% at 10 uM..

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

    Biological Activity

    CL-82198 is a potent, selective inhibitor of MMP-13 (89% inhibition at 10 ug/mL), displays no activity at MMP-1, MMP-9 and TACE, significantly reduces the migration of LS174 cells by 55% at 10 uM.

    Physicochemical Properties

    M.Wt 338.832
    Formula C17H23ClN2O3
    Appearance Solid
    CAS No.
    Storage
    Solide Powder
    -20 °C 12 Months; 4°C 6 Months
    In Solvent
    -80 °C 6 Months; -20°C 6 Months
    Shipping
    Solubility

    10 mM in DMSO
    Chemical Name/SMILES

    N-[4-(4-Morpholinyl)butyl]-2-benzofurancarboxamide hydrochloride

    References

    1. Chen et al, et al. J.Am.Chem.Soc. 2012.

    2. Rath T, et al. Oncol Lett. 2011 May;2(3):483-488.

    3. Hernández Ríos M, et al. J Clin Periodontol. 2009 Dec;36(12):1011-7.

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