Catalog No.: PC-61021Not For Human Use, Lab Use Only.
CLK inhibitor T3 (T3) is a highly potent, selective, and cell-based stable CDC-like kinase (CLK) inhibitor with 0.67, 15 and 110 nM for CLK1,2 and 3, respectively.
CLK inhibitor T3 (T3) is a highly potent, selective, and cell-based stable CDC-like kinase (CLK) inhibitor with 0.67, 15 and 110 nM for CLK1,2 and 3, respectively.
CLK inhibitor T3 (T3) displays 200-300-fold selectivity over other dual specificity kinases such as DYRK1A and DYRK1B.
CLK inhibitor T3 (T3) induces dose-dependent reduction in exon recognition and exhibits an overlapping, but greater effect on transcriptome splicing compared to KH-CB19.
