| Cat. No. |
Product Name |
Information |
| PC-22056 |
CLK2 inhibitor LQ23
CLK2 inhibitor
|
CLK2 inhibitor LQ23 is a potent, selective cdc2-like kinase 2 (CLK2) inhibitor with IC50 of 1.4 nM, >70-fold selecitve over CLK3. |
| PC-21435 |
SM04755
CLK inhibitor
|
Teplinovivint (SM04755) is a small molecule canonical Wnt signaling inhibitor, potently inhibited CLK2, CLK3, and DYRK1A with IC50 of 5.0 nM, 48.6 nM and 3.5 nM, respectively. |
| PC-20895 |
MW01
CLK inhibitor
|
MW01 is a specific inhibitor for DNA damage-induced NF-κB activity, inhibits CLK2 and CLK4 with IC50 of 360 and 14.1 nM, does not inhibit CLK3. |
| PC-20894 |
MW05
CLK inhibitor
|
MW05 is a specific inhibitor for DNA damage-induced NF-κB activity, inhibits CLK2 and CLK4 with IC50 of 1400 and 307 nM, does not inhibit CLK3. |
| PC-20474 |
GPS192
CLK inhibitor
|
GPS192 (GPS 167) is a specific small molecule splicing regulator SRSF10 inhibitor, modulates BCLAF1 splicing with IC50 of 2 uM in human colorectal HCT116 cells, directly inhibits CLK1, CLK2 and CLK4, but not SRPK1 and DYRK1A. |
| PC-73374 |
CLK4 inhibitor 96
CLK4 inhibitor
|
CLK4 inhibitor 96 is a novel potent CLK4 inhibitor with IC50 of 57.5 nM. |
| PC-73373 |
GPS167
CLK inhibitor, SRSF10 inhibitor
|
GPS167 is a specific small molecule splicing regulator SRSF10 inhibitor, modulates BCLAF1 splicing with IC50 of 2 uM in human colorectal HCT116 cells, directly inhibits CLK1, CLK2 and CLK4, but not SRPK1 and DYRK1A. |
| PC-72906 |
Ipivivint
CLK inhibitor
|
Ipivivint is a potent, selective CLK inhibitor, inhibits Wnt pathway signaling gene expression through inhibiting CLK activity and serine and SRSF phosphorylation. |
| PC-72778 |
TG003
CLK inhibitor
|
TG003 (TG-003) is a potent, specific, reversible, and ATP-competitive inhibitor of Cdc2-like kinase (CLK) with IC50 of 20, 200 and 15 nM for mClk1, 2 and 4 respectively, and >10 uM for mClk3 |
| PC-72099 |
Cirtuvivint
CLK inhibitor
|
Cirtuvivint (SM08502) is a novel potent, selective inhibitor of CDC-like kinase (CLK) with IC50 of 2/22 nM against CLK2/3. |
| PC-35987 |
MU1210
CLK inhibitor
|
MU1210 (MU-1210) is a potent and highly selective inhibitor of cdc-like kinases (CLKs) with IC50 of 51 nM (cellular BRET for CLK1). |
| PC-35359 |
CLK2 inhibitor Indazole 1
CLK2 inhibitor
|
CLK2 inhibitor Indazole1 is a novel potent, selective inhibitor of CLK2 with IC50 of 2.7 nM, 60-fold selectivity over PKA and >600-fold selectivity over a panel of 34 kinases. |
