| Cat. No. |
Product Name |
Information |
| PC-61022 |
CC-671
Mps1/CLK2 inhibitor
|
CC-671 (CC671) is a potent, selective, dual TTK (Mps1)/CLK2 inhibitor with IC50 of 5/3 nM, respectively. |
| PC-61021 |
CLK inhibitor T3
CLK inhibitor
|
CLK inhibitor T3 (T3) is a highly potent, selective, and cell-based stable CDC-like kinase (CLK) inhibitor with 0.67, 15 and 110 nM for CLK1,2 and 3, respectively. |
| PC-60504 |
SM04690
CLK inhibitor
|
Adavivint (Lorecivivint, SM04690) is a novel small molecule Wnt pathway inhibitor with EC50 of 3 nM in vitro, potently inhibits CLK2 and DYRK1A with IC50 of 5.8 and 26.9 nM, respectively. |
| PC-23183 |
LBM22
CLK2 inhibitor
|
LBM22 is a potent, small molecule inhibitor of CDC2-like kinase 2 (CLK2) with IC50 of 3.9 nM, exhibits broad suppression of NSCLC cells proliferation and induction of apoptosis. |
| PC-22323 |
Compound 670551
CLK2 inhibitor
|
Compound 670551 is a potent Cdc2-like kinase 2 (CLK2) inhibitor with IC50 of 619.7 nM, inhibits CLK activity by 96% at 10 uM. |
| PC-21434 |
CTX-712
CLK2 inhibitor
|
CTX-712 is an orally available and highly potent cdc2-like kinase (CLK) inhibitor with IC50 of 1.4 nM (CLK2). |
| PC-21433 |
CLK1 inhibitor 25
CLK inhibitor
|
CLK1 inhibitor 25 is a potent and selective inhibitor of cdc2-like kinase 1 (CLK1) with IC50 of 2 nM, 69-fold selective over DYRK1A. |
| PC-21432 |
SGC-CLK-1N
CLK inhibitor
|
SGC-CLK-1N (CAF-225) is the negative control compound of CLK1/2/4 inhibitor SGC-CLK-1 (CAF-170). |
| PC-21431 |
SGC-CLK-1
CLK inhibitor
|
SGC-CLK-1 (CAF-170) is a potent and selective inhibitor of Cdc2-Like kinases CLK1, 2 and 4 with binding IC50 values of 13 nM, 4 nM, and 46 nM, resepctively. |
| PC-20985 |
Leucettinib-92
DYRK/CLK inhibitor
|
Leucettinib-92 is a potent DYRK/CLK inhibitor, inhibits CLK1, CLK2, CLK4, DYRK1A and DYRK1B with IC50 of 9.2, 6, 6, 1.2 and 1.8 nM, respectively. |
| PC-20756 |
ML315
CLK inhibitor
|
ML315 is a small molecule inhibitor of the cdc2-like (Clk) and dual specificity tyrosine phosphorylation-regulated (Dyrk) kinases with IC50 of 68, 231, >10,000, 68, 282 and 1156 nM for CLK1/2/3/4 and DYRK1/2, respectively. |
