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Chemical Structure : Compound 670551
Catalog No.: PC-22323Not For Human Use, Lab Use Only.
Compound 670551 is a potent Cdc2-like kinase 2 (CLK2) inhibitor with IC50 of 619.7 nM, inhibits CLK activity by 96% at 10 uM.
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Compound 670551 is a potent Cdc2-like kinase 2 (CLK2) inhibitor with IC50 of 619.7 nM, inhibits CLK2 activity by 96% at 10 uM.
Compound 670551 inhibits TNBC cell growth and survival.
Compound 670551 downregulates serine/arginine‐rich splicing factor (SRSF) phosphorylation and induces cell apoptosis.
| M.Wt | 288.35 | |
| Formula | C18H16N4 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Cheng-Chiao Huang, et al. Protein Sci. 2024 Jun;33(6):e5004.
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