| Cat. No. |
Product Name |
Information |
| PC-35047 |
T-025
CLK inhibitor
|
T-025 (T025, CLK inhibitor T-025) is an orally available, potent inhibitor of Cdc2-like kinases (CLKs) with Kd of 4.8, 0.096, 6.5, and 0.61 nM for CLK1, CLK2, CLK3, and CLK4, also inhibits DYRK1A and DYRK1B with IC50 of 0.074 and 1.5 nM. |
| PC-63478 |
Leucettamine B
CLK1 inhibitor
|
Leucettamine B is a potent inhibitor of CLK1 (IC50=15 nM), Dyrk1A (IC50=40 nM), and Dyrk2 (IC50=35 nM) and a moderate inhibitor of CLK3 (IC50=4.5 uM).. |
| PC-63477 |
ML197
CLK inhibitor
|
ML197 (NCGC00185963) is a potent, selective small molecule inhibitor of Cdc2-like kinases (CLK) and DYRK with IC50 of 96/40/206 nM for CLK1/CLK4/Dyrk1A, respectively. |
| PC-63470 |
KuWal151
CLK1/2/4 inhibitor
|
KuWal151 is a potent, selective cdc2-like kinase (CLK) inhibitor with IC50 of 88/510/28 nM for CLK1/2/4, respectively. |
| PC-63265 |
K00546
CLK1/3 inhibitor
|
K00546 is a potent inhibitor of the CDC2-like kinase CLK1 and CLK3 with IC50 of 8.9 and 29.2 nM, respectively. |
| PC-43237 |
KH-CB19
CLK1/4 inhibitor
|
KH-CB19 is a potent and highly specific inhibitor of CDC2-like kinase isoforms 1 and 4 (CLK1/CLK4) with IC50 of 20 nM (CLK1), displays almost 100-fold selectivity against the CLK3 isoform. |
| PC-61029 |
ML167
CLK4 inhibitor
|
ML167 is a potent, selective CDC-like kinase 4 (CLK4) inhibitor with IC50 of 136 nM, >10-fold selectivity over Clk1, Clk2, Clk3, Dyrk1A/1B. |
| PC-61028 |
CGP-74514A
CDK1/CLK inhibitor
|
CGP-74514A is a cell permeable, potent, and selective inhibitor of CDK1/cyclin B with IC50 of 25 nM, and CLK1, CLK2, CLK4 inhibitor. |
| PC-61027 |
SRI-29329
CLK inhibitor
|
SRI-29329 (SRI29329) is a potent, specific CDC-like kinase (CLK) inhibitor with IC50 of 78, 16 and 86 nM for CLK1, 2 and 4, respectively. |
| PC-61026 |
CLK inhibitor 2
CLK1/2 inhibitor
|
CLK inhibitor 2 is a potent, selective inhibitor of cdc2-like kinase CLK1 and CLK2 with IC50 of 1.1 and 2.4 nM, respectively. |
| PC-61025 |
Leucettine L41
CLK/DYRK inhibitor
|
Leucettine L41 is a novel potent cdc2-like kinase (CLKs) and DYRKs inhibitor with IC50 of 40, 35 and 15 nM for DYRK1A, DYRK2 and CLK1, respectively. |
| PC-61023 |
TG693
CLK1 inhibitor
|
TG693 is an orally available, selective, ATP-competitive CLK1 inhibitor with IC50 of 112.6 nM. |
