K00546 |CAS:443798-47-8 Probechem Biochemicals

Chemical Structure : K00546

CAS No.: 443798-47-8

Catalog No.: PC-63265Not For Human Use, Lab Use Only.

K00546 is a potent inhibitor of the CDC2-like kinase CLK1 and CLK3 with IC50 of 8.9 and 29.2 nM, respectively.

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Biological Activity

K00546 is a potent inhibitor of the CDC2-like kinase CLK1 and CLK3 with IC50 of 8.9 and 29.2 nM, respectively.

M.Wt	425.433
Formula	C15H13F2N7O2S2
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	5-amino-N-(2,6-difluorophenyl)-3-((4-sulfamoylphenyl)amino)-1H-1,2,4-triazole-1-carbothioamide

1. Fedorov O, et al. Chem Biol. 2011 Jan 28;18(1):67-76.

2. Prak K, et al. Biochemistry. 2016 Jan 26;55(3):608-17.