Chemical Structure : K00546
CAS No.: 443798-47-8
Catalog No.: PC-63265Not For Human Use, Lab Use Only.
K00546 is a potent inhibitor of the CDC2-like kinase CLK1 and CLK3 with IC50 of 8.9 and 29.2 nM, respectively.
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K00546 is a potent inhibitor of the CDC2-like kinase CLK1 and CLK3 with IC50 of 8.9 and 29.2 nM, respectively.
M.Wt | 425.433 | |
Formula | C15H13F2N7O2S2 | |
Appearance | Solid | |
Storage |
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Solubility |
10 mM in DMSO |
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Chemical Name/SMILES |
5-amino-N-(2,6-difluorophenyl)-3-((4-sulfamoylphenyl)amino)-1H-1,2,4-triazole-1-carbothioamide |
1. Fedorov O, et al. Chem Biol. 2011 Jan 28;18(1):67-76.
2. Prak K, et al. Biochemistry. 2016 Jan 26;55(3):608-17.
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