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Request The Product List ofCdc2-like Kinase (CLK) Cdc2-like Kinase (CLK)

Cat. No. Product Name Information
PC-73373

GPS167

CLK inhibitor, SRSF10 inhibitor

GPS167 is a specific small molecule splicing regulator SRSF10 inhibitor, modulates BCLAF1 splicing with IC50 of 2 uM in human colorectal HCT116 cells, directly inhibits CLK1, CLK2 and CLK4, but not SRPK1 and DYRK1A.
PC-72906

Ipivivint

CLK inhibitor

Ipivivint is a potent, selective CLK inhibitor, inhibits Wnt pathway signaling gene expression through inhibiting CLK activity and serine and SRSF phosphorylation.
PC-72778

TG003

CLK inhibitor

TG003 (TG-003) is a potent, specific, reversible, and ATP-competitive inhibitor of Cdc2-like kinase (CLK) with IC50 of 20, 200 and 15 nM for mClk1, 2 and 4 respectively, and >10 uM for mClk3
PC-72581

CaNDY

CLK inhibitor

CaNDY is a highly potent rectifier of the aberrant splicing, potently inhibits DYRK1A, DYRK1B, CLK1/CLK2/ with IC50 of 21.6/68.3/116 nM in in vitro kinase assays.
PC-72099

Cirtuvivint

CLK inhibitor

Cirtuvivint (SM08502) is a novel potent, selective inhibitor of CDC-like kinase (CLK) with IC50 of 2/22 nM against CLK2/3.
PC-35987

MU1210

CLK inhibitor

MU1210 (MU-1210) is a potent and highly selective inhibitor of cdc-like kinases (CLKs) with IC50 of 51 nM (cellular BRET for CLK1).
PC-35359

CLK2 inhibitor Indazole 1

CLK2 inhibitor

CLK2 inhibitor Indazole1 is a novel potent, selective inhibitor of CLK2 with IC50 of 2.7 nM, 60-fold selectivity over PKA and >600-fold selectivity over a panel of 34 kinases.
PC-35047

T-025

CLK inhibitor

T-025 (T025, CLK inhibitor T-025) is an orally available, potent inhibitor of Cdc2-like kinases (CLKs) with Kd of 4.8, 0.096, 6.5, and 0.61 nM for CLK1, CLK2, CLK3, and CLK4, also inhibits DYRK1A and DYRK1B with IC50 of 0.074 and 1.5 nM.
PC-63478

Leucettamine B

CLK1 inhibitor

Leucettamine B is a potent inhibitor of CLK1 (IC50=15 nM), Dyrk1A (IC50=40 nM), and Dyrk2 (IC50=35 nM) and a moderate inhibitor of CLK3 (IC50=4.5 uM)..
PC-63477

ML197

CLK inhibitor

ML197 (NCGC00185963) is a potent, selective small molecule inhibitor of Cdc2-like kinases (CLK) and DYRK with IC50 of 96/40/206 nM for CLK1/CLK4/Dyrk1A, respectively.
PC-63470

KuWal151

CLK1/2/4 inhibitor

KuWal151 is a potent, selective cdc2-like kinase (CLK) inhibitor with IC50 of 88/510/28 nM for CLK1/2/4, respectively.
PC-63265

K00546

CLK1/3 inhibitor

K00546 is a potent inhibitor of the CDC2-like kinase CLK1 and CLK3 with IC50 of 8.9 and 29.2 nM, respectively.

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