CMFT

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Chemical Structure : CMFT

Catalog No.: PC-22448Not For Human Use, Lab Use Only.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

CMFT is a a small molecule inhibitor of the functional interaction between the transcription factor ICBP90 (a.k.a. UHRF1) and the MIF-794 CATT5-8 promoter microsatellite, inhibits MIF mRNA expression in a -794 CATT5-8 length-dependent manner with an IC50 of 470 nM.
CMFT preferentially reduces ICBP90-dependent MIF mRNA and protein expression in high-genotypic versus low-genotypic MIF - expressing macrophages.

Physicochemical Properties

M.Wt	316.27
Formula	C15H12N2O6
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	1-carbomethoxy-5-formyl-4,6,8-trihydroxyphenazine

References

1. Li J, et al. J Biol Chem. 2024 Jun 3:107443.

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CMFT

Biological Activity

Physicochemical Properties

References

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