Chemical Structure : CP-31398 dihydrochloride
CAS No.: 1217195-61-3
Catalog No.: PC-62082Not For Human Use, Lab Use Only.
CP-31398 (CP31398) dihydrochloride is a small molecule p53 reactivator that protects p53 from thermal denaturation, not only reactivates mutant p53 but also induces stabilization of wild type p53.
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CP-31398 (CP31398) dihydrochloride is a small molecule p53 reactivator that protects p53 from thermal denaturation, not only reactivates mutant p53 but also induces stabilization of wild type p53.
CP-31398 shows anti-tumor activity in vivo in a transgenic UPII-SV40T mouse model of bladder transitional cell carcinoma.
M.Wt | 435.39 | |
Formula | C22H26N4O.2HCl | |
Appearance | Solid | |
Storage |
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Solubility |
10 mM in DMSO |
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Chemical Name/SMILES |
N'-[2-[2-(4-Methoxyphenyl)ethenyl]-4-quinazolinyl]-N,N-dimethyl-1,3-propanediamine dihydrochloride |
1. Foster BA, et al. Science. 1999 Dec 24;286(5449):2507-10.
2. Madka V, et al. Neoplasia. 2013 Aug;15(8):966-74.
3. Wang W, et al. Mol Cell Biol. 2003 Mar;23(6):2171-81.
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