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CU-115

Chemical Structure : CU-115

CAS No.: 2471982-20-2

CU-115 (CU115)

Catalog No.: PC-72052Not For Human Use, Lab Use Only.

CU-115 is a novel potent, selective TLR8 antagonist (inhibitor) with IC50 of 1.4 uM, shows no significant inhibitory effect on TLR7 (IC50>50 uM).

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

CU-115 is a novel potent, selective TLR8 antagonist (inhibitor) with IC50 of 1.4 uM, shows no significant inhibitory effect on TLR7 (IC50>50 uM).

Physicochemical Properties

M.Wt 569.217
Formula C21H11F7INO2
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

Benzamide, N-[4-[3,5-bis(trifluoromethyl)phenoxy]phenyl]-2-fluoro-6-iodo-

References

1. Rosaura Padilla-Salinas, et al. J Med Chem. 2019 Nov 27;62(22):10221-10244.

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