Chemical Structure : CU-115
CAS No.: 2471982-20-2
Catalog No.: PC-72052Not For Human Use, Lab Use Only.
CU-115 is a novel potent, selective TLR8 antagonist (inhibitor) with IC50 of 1.4 uM, shows no significant inhibitory effect on TLR7 (IC50>50 uM).
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CU-115 is a novel potent, selective TLR8 antagonist (inhibitor) with IC50 of 1.4 uM, shows no significant inhibitory effect on TLR7 (IC50>50 uM).
M.Wt | 569.217 | |
Formula | C21H11F7INO2 | |
Appearance | Solid | |
Storage |
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Solubility |
10 mM in DMSO |
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Chemical Name/SMILES |
Benzamide, N-[4-[3,5-bis(trifluoromethyl)phenoxy]phenyl]-2-fluoro-6-iodo- |
1. Rosaura Padilla-Salinas, et al. J Med Chem. 2019 Nov 27;62(22):10221-10244.
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