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CU-72

Chemical Structure : CU-72

CAS No.: 2471977-91-8

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CU-72 (CU72)

Catalog No.: PC-73105Not For Human Use, Lab Use Only.

CU-72 is a potent, selective TLR7/8 dual inhibitor with IC50 of 5.10 and 2.87 uM, respectively.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

    Biological Activity

    CU-72 is a potent, selective TLR7/8 dual inhibitor with IC50 of 5.10 and 2.87 uM, respectively.

    Physicochemical Properties

    M.Wt 410.753
    Formula C19H11ClF4N2O2
    Appearance Solid
    CAS No.
    Storage
    Solide Powder
    -20°C 12 Months; 4°C 6 Months
    In Solvent
    -80°C 6 Months; -20°C 6 Months
    Shipping
    Solubility

    10 mM in DMSO
    Chemical Name/SMILES

    2-Chloro-6-fluoro-N-(4-{[5-(trifluoromethyl)pyridin-3-yl]oxy}phenyl)benzamide

    References

    1. Padilla-Salinas R, et al. J Med Chem. 2019 Nov 27;62(22):10221-10244.

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