Welcome to ProbeChem!Global Supplier of Chemical Probes, Inhibitors & Agonists.
Chemical Structure : CU-76
Catalog No.: PC-73123Not For Human Use, Lab Use Only.
CU-76 (cGAS inhibitor CU-76) is a small-molecule human cGAS (hcGAS) inhibitor with IC50 of 0.24 uM.
Bulk size, bulk discount!
E-mail: sales@probechem.com
Tech Support: tech@probechem.com
CU-76 (cGAS inhibitor CU-76) is a small-molecule human cGAS (hcGAS) inhibitor with IC50 of 0.24 uM.
CU-76 selectively inhibit the DNA pathway in human cells but have no effect on the RIG-I-MAVS or Toll-like receptor pathways.
CU-76 represents a new class of hcGAS inhibitor with activity in cells and chemical scaffold for designing probes to study cGAS function and development of autoimmune therapeutics.
| M.Wt | 407.119 | |
| Formula | C11H8F2IN5O2 | |
| Appearance | Solid | |
| Storage |
|
|
| Solubility |
10 mM in DMSO |
|
1. Padilla-Salinas R, et al. J Org Chem. 2019 Dec 12. doi: 10.1021/acs.joc.9b02666.
Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright
