| Cat. No. |
Product Name |
Information |
| PC-23640 |
cGAS inhibitor 36
cGAS inhibitor
|
cGAS inhibitor 36 is a potent, orally bioavailable inhibitor of cyclic GMP-AMP synthase (cGAS) with biochemical IC50 of 32 nM and 5.8 nM for h-cGAS and m-cGAS respectively. |
| PC-49403 |
cGAS inhibitor 3
cGAS inhibitor
|
cGAS inhibitor 3 is a potent, selective and covalent inhibitor of cyclic GMP-AMP synthase (cGAS) with cellular IC50 of 0.51 uM. |
| PC-73361 |
G150
cGAS inhibitor
|
G150 is a potent, specific human cyclic GMP-AMP synthase (cGAS) small-molecule inhibitor with IC50 of 10.2 nM, shows no inhibition against m-cGAS. |
| PC-73360 |
G140
cGAS inhibitor
|
G140 is a potent, specific human cGAS small-molecule inhibitor with IC50 of 14.0 nM and 442 nM for h-cGAS and m-cGAS, respectively. |
| PC-73123 |
CU-76
cGAS inhibitor
|
CU-76 (cGAS inhibitor CU-76) is a small-molecule human cGAS (hcGAS) inhibitor with IC50 of 0.24 uM. |
| PC-61340 |
PF-06928215
cGAS inhibitor
|
PF-06928215 (PF06928215) is a high affinity Cyclic GMP-AMP synthase (cGAS) inhibitor with Kd of 200 nM, IC50 of 4.9 uM. |
| PC-60018 |
RU.521
cGAS inhibitor
|
RU.521 (RU521, RU-320521) is a potent, selective cyclic GMP-AMP synthase (cGAS) inhibitor with Kd of 36.2 nM. |
| PC-24705 |
XL-3158
cGAS inhibitor
|
XL-3158 is a potent, selective, cross-species, allosteric inhibitor of cyclic GMP-AMP synthase (cGAS), has binding affinity to the catalytic domain of human cGAS (h-cGASCD) with a Kd of 7.19 μM, effectively inhibits cGAS-DNA condensate formation. |
| PC-24704 |
XL-3156
cGAS inhibitor
|
XL-3156 is a potent, selective, cross-species, allosteric inhibitor of cyclic GMP-AMP synthase (cGAS), targets both the orthosteric and allosteric sites, effectively inhibits cGAS-DNA phase separation. |
