Chemical Structure : PF-06928215
CAS No.: 2378173-15-8
Catalog No.: PC-61340Not For Human Use, Lab Use Only.
PF-06928215 (PF06928215) is a high affinity Cyclic GMP-AMP synthase (cGAS) inhibitor with Kd of 200 nM, IC50 of 4.9 uM.
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PF-06928215 (PF06928215) is a high affinity Cyclic GMP-AMP synthase (cGAS) inhibitor with Kd of 200 nM, IC50 of 4.9 uM.
M.Wt | 380.404 | |
Formula | C20H20N4O4 | |
Appearance | Solid | |
Storage |
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Solubility |
10 mM in DMSO |
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Chemical Name/SMILES |
(1R,2S)-2-(7-hydroxy-5-phenylpyrazolo[1,5-a]pyrimidine-3-carboxamido)cyclohexane-1-carboxylic acid |
1. Hall J, et al. PLoS One. 2017 Sep 21;12(9):e0184843.
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