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PF-06928215

Chemical Structure : PF-06928215

CAS No.: 2378173-15-8

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PF-06928215 (PF 06928215, PF06928215)

Catalog No.: PC-61340Not For Human Use, Lab Use Only.

PF-06928215 (PF06928215) is a high affinity Cyclic GMP-AMP synthase (cGAS) inhibitor with Kd of 200 nM, IC50 of 4.9 uM.

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5 mg $178 In stock
10 mg $278 In stock
25 mg $498 In stock
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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

PF-06928215 (PF06928215) is a high affinity Cyclic GMP-AMP synthase (cGAS) inhibitor with Kd of 200 nM, IC50 of 4.9 uM.

Physicochemical Properties

M.Wt 380.404
Formula C20H20N4O4
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

(1R,2S)-2-(7-hydroxy-5-phenylpyrazolo[1,5-a]pyrimidine-3-carboxamido)cyclohexane-1-carboxylic acid

References

1. Hall J, et al. PLoS One. 2017 Sep 21;12(9):e0184843.

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