Chemical Structure : cGAS inhibitor XQ2B
CAS No.: 2104728-28-9
Catalog No.: PC-26963Not For Human Use, Lab Use Only.
cGAS inhibitor XQ2B is potent, selective cyclopeptide inhibitor of Cyclic GMP-AMP synthase (cGAS), specifically binds to the DNA binding site of cGAS and blocks the binding of dsDNA with cGAS, subsequently inhibits dsDNA-induced liquid phase condensation and activation of cGAS, inhibits HSV-1-induced antiviral immune responses and enhances HSV-1 infection in vitro and in vivo.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 5 mg | $198 | In stock | |
| 10 mg | $298 | In stock | |
| 25 mg | $488 | In stock | |
| 50 mg | Get quote | ||
| 100 mg | Get quote |
Bulk size, bulk discount!
E-mail: sales@probechem.com
Tech Support: tech@probechem.com
cGAS inhibitor XQ2B is potent, selective cyclopeptide inhibitor of Cyclic GMP-AMP synthase (cGAS), specifically binds to the DNA binding site of cGAS and blocks the binding of dsDNA with cGAS, subsequently inhibits dsDNA-induced liquid phase condensation and activation of cGAS, inhibits HSV-1-induced antiviral immune responses and enhances HSV-1 infection in vitro and in vivo.
| M.Wt | 1201.46 | |
| Formula | C59H92N16O11 | |
| Appearance | Solid | |
| Storage |
|
|
| Solubility |
10 mM in DMSO |
|
| Chemical Name/SMILES |
Cyclo (D-Phe-Ala-Thr-Arg-Leu-D-Phe-Pro-Val-Arg-Leu) |
|
1. Wang X, et al. Nat Commun. 2023 Oct 2;14(1):6132.

Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright