RU-0610270

Chemical Structure : RU-0610270

Catalog No.: PC-25368Not For Human Use, Lab Use Only.

RU-0610270 is a potent small molecule inhibitor of human cyclic GMP-AMP synthase (cGAS) with IC50 of 1.88 uM.

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Biological Activity

RU-0610270 is a potent small molecule inhibitor of human cyclic GMP-AMP synthase (cGAS) with IC50 of 1.88 uM.

M.Wt	412.30
Formula	C17H18BrNO4S
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	N-((3-bromo-4-ethoxyphenyl)sulfonyl)-2-(p-tolyl)acetamide

1. Alarcón-Espósito J, et al. bioRxiv [Preprint]. 2025 Aug 22:2025.08.18.670979.