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CUDA

Chemical Structure : CUDA

CAS No.: 479413-68-8

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CUDA (sEH inhibitor)

Catalog No.: PC-70252Not For Human Use, Lab Use Only.

CUDA is a potent inhibitor of sEH (soluble epoxide hydrolase) with IC50 of 11.1 nM and 112 nM for mouse sEH and human sEH, respectively.

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10 mg $78 In stock
25 mg $138 In stock
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100 mg $358 In stock
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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

CUDA is a potent inhibitor of sEH (soluble epoxide hydrolase) with IC50 of 11.1 nM and 112 nM for mouse sEH and human sEH, respectively.
CUDA blocks conversion of 1 uM 14,15-EET to 14,15-DHET by 94% at 10 uM in COS-7 cells.
CUDA activates PPARα 8-fold at a concentration of 10 uM but exhibits no affect on PPARδ or PPARγ.

Physicochemical Properties

M.Wt 340.5
Formula C19H36N2O3
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

12-[[(cyclohexylamino)carbonyl]amino]-dodecanoic acid

References

1. Morisseau C, et al. Biochem Pharmacol. 2002 May 1;63(9):1599-608.

2. Fang X, et al. J Pharmacol Exp Ther. 2005 Jul;314(1):260-70.

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